Principal Advisor: Associate Professor Severine Navarro

Email: severine.navarro@qimrberghofer.edu.au

Phone: 07 3362 0487

Organisational unit: QIMR Berghofer, School of Biomedical Sciences

Asthma is characterised by an abhorrent immune response to an allergen that is permitted due to a defect in regulatory T (Treg) cell numbers and/or function. We propose to better understand the role of the gut microbiome in the induction of Tregs by identifying their antigen specificity and potential recognition of bacterial antigens. This project will provide essential insights in the mechanisms of tolerance. You will be trained in immunology and immunology-based assays using in vivo, ex vivo and in vitro approaches. Flow cytometry, cell sorting and single cell sequencing will also be used in combination to some molecular biology techniques.