Currently, over 50% of patients with severe infection in ICU will die. 

The UQ critical care research team is working to improve this statistic and brings together a range of expertise from across UQ and the Royal Brisbane and Women’s Hospital (RBWH), in the areas of drug dosing, burns, anaesthesia and emergency medicine. 

Commitment to improving critical care around the world

Our team’s research has been instrumental in changing antibiotic prescribing habits for critically ill patients around the world. Therapeutic Drug Monitoring (TDM) for problematic patients allows for personalised dosing regimens for problematic patients, particularly those in intensive care. 

The Burns, Trauma, and Critical Care Research Centre (BTCCRC) was established in 2004, as a collaborative venture between the Royal Brisbane and Women’s Hospital (RBWH) Burns and Intensive Care Units and UQ Medicine. It was created in response to the 2002 Bali bombings, which brought national attention the need to improve the treatment of and outcomes for critically ill patients. 

The Centre for Children's Burns and Trauma Research was established in 1999 by Professor Roy Kimble, and is one of the leading burns and trauma research groups in Australia. It aims to prevent children from sustaining traumatic injuries such as burns and to provide the best evidence-based treatment for children with traumatic injuries. 

The Critical Care Research Group (CCRG) was established in 2004 by Professor John Fraser, and aims to improve patient outcomes for the critically ill through the development of new and innovative technology to improve clinical practice. Based in Australia’s leading cardiothoracic hospital, The Prince Charles Hospital, it consists of three streams (Engineering, Science and Clinical). The research is clinician-driven and aims to address gaps in current practice to aid clinical decision-making and patient management, resulting in improved levels of care provided to acutely ill patients, improved patient outcomes and reduced healthcare costs. CCRG is the largest group of its kind in Australasia, with more than 70 full time members. The group has extensive worldwide collaborations and provides opportunities for partnering with and attracting some of the world’s leading academics to Queensland. The group was designated as the first NHMRC Centre of Research Excellence (CRE) in mechanical assisted devices, and through the CRE, established an extensive collaborative network with other research institutions and industry partners.

Combating superbugs and antibiotic resistance

Over prescription of antibiotics has contributed significantly to antibiotic resistance, allowing superbugs to emerge. Scientists are now under huge pressure to discover new antibiotics to stay ahead of the rise in antibiotic resistance.

The REDUCE Centre for Research Excellence was established in 2015 and aims to redefine antibiotic use and overcome antibiotic resistance. Research will focus on finding new ways to fight diseases when bacteria no longer responds to antibiotic treatment.

Critical care research leaders