Skin and skin cancer

Our skin and skin cancer research aims to improve patient outcomes and is conducted by a number of interdisciplinary teams containing both researchers and clinicians.

Our work has great implications for public health and is focused on the development of new health delivery models for skin diseases, with a special emphasis on improving the patient’s experience.

Our skin and skin cancer research includes:

  • Melanoma
  • Keratinocyte cancer
  • Precancerous skin lesions
  • Response of skin to UV radiation
  • Pigmentation
  • Viruses, vaccines and skin immunology
  • Wound healing
  • Hair and regenerative medicine
  • Skin cancer epidemiology
  • Telemedicine for remote management of skin and skin cancer

In Australia, the incidence of skin cancer and melanoma is one of the highest in the world and our Brisbane based researchers are world leaders in skin cancer and melanoma research, one of the strength areas for the Faculty.

Further information about skin research in the Faculty of Medicine can be found here.

Our skin research is particularly strong in the following area:

Skin cancer

Cell imaging

These videos of real-time imaging of melanoma cells are used to investigate the biology of the tumour and the role of differential subpopulations of melanoma cells in melanomagenesis.  It illustrates through a colour changing method that tumour cells can grow at different rates, a dormant core (red) surrounded by actively growing cell (a mix of red, yellow and green).  This 3D melanoma model could provide the key to anti-cancer treatment with response rates to drugs differing in dormant and growing cells.  The aim is to develop novel therapeutic approaches to treatment by simultaneously targeting these differential subpopulations.

Confocal microscopy

Multiphoton microscopy

Haass, Nikolas K., Beaumont, Kimberley A., Hill, David S., Anfosso, Andrea, Mrass, Paulus, Munoz, Marcia A., Kinjyo, Ichiko and Weninger, Wolfgang (2014) Real-time cell cycle imaging during melanoma growth, invasion, and drug response. Pigment Cell and Melanoma Research, 27 5: 764-776. doi:10.1111/pcmr.12274